Integration of PK/PD for dose optimization of Cefquinome against Staphylococcus aureus causing septicemia in cattle
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منابع مشابه
Integration of PK/PD for dose optimization of Cefquinome against Staphylococcus aureus causing septicemia in cattle
Cefquinome is a fourth generation cephalosporin with antimicrobial activity against gram negative and gram positive bacterial species, including Staphylococcus aureus. The aim of our study was to observe the ex-vivo activity of cefquinome against Staphylococcus aureus strains by using bovine serum from intravenously treated cattle. Cefquinome kinetics were measured by liquid chromatography and ...
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Pharmacokinetic/Pharmacodynamic Correlation of Cefquinome Against Experimental Catheter-Associated Biofilm Infection Due to Staphylococcus aureus
Biofilm formations play an important role in Staphylococcus aureus pathogenesis and contribute to antibiotic treatment failures in biofilm-associated infections. The aim of this study was to evaluate the pharmacokinetic/pharmacodynamic (PK/PD) profiles of cefquinome against an experimental catheter-related biofilm model due to S. aureus, including three clinical isolates and one non-clinical is...
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ژورنال
عنوان ژورنال: Frontiers in Microbiology
سال: 2015
ISSN: 1664-302X
DOI: 10.3389/fmicb.2015.00588